Dinaciclib
Dinaciclib

Dinaciclib

Product Name: Dinaciclib
Synonyms: 1-[3-ethyl-7-[[(1-oxido-3-pyridinyl)methyl]amino]pyrazolo[1,5-a]pyrimidin-5-yl]-2S-piperidineethanol SCH 727965Web Site click
Product Overview: A pan-CDK inhibitor (IC50s = 3, 1, 1, and 4 nM for CDK1, CDK2, CDK5, and CDK9, respectively) that inhibits DNA synthesis in A2780 ovarian cancer cells (IC50 = 4 nM); 5 mg/kg prevents tumor growth by 50% in an A2780 ovarian carcinoma mouse xenograft model;
Shipping: wet ice
CAS NO: Product: D-JNKI-1
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C21H28N6O2
SMILES: OCC[[email protected]]1N(C2=NC3=C(CC)C=NN3C(NCC4=CC=C[N+]([O-])=C4)=C2)CCCC1HCV inhibitors
Molecular Weight: 396.5
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/55/12/5753.abstract