CX-6258
CX-6258

CX-6258

Product Name: CX-6258
Synonyms: (3E)-5-chloro-3-[[5-[3-[(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)carbonyl]phenyl]-2-furanyl]methylene]-1,3-dihydro-2H-indol-2-one Pim-Kinase InhibitWeb Site:Medchemexpress
Product Overview: A potent, reversible, orally bioavailable inhibitor of Pim-1, -2, and -3 (IC50s = 5, 25, and 16 nM, respectively); dose-dependently blocks the phosphorylation of the Pim targets Bad, 4E-BP1, and NKX3.1; acts synergistically with chemotherapeutic drugsThe
Shipping: wet ice
CAS NO: 32780-64-6 Product: Labetalol (hydrochloride)
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C26H24ClN3O3
SMILES: O=C(N1CCCN(C)CC1)C2=CC=CC(C3=CC=C(/C=C4C(NC5=C/4C=C(Cl)C=C5)=O)O3)=C2Hedgehog inhibitors
Molecular Weight: 461.9
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/56/8/4519.abstract