Product Name: CO-1686
Synonyms: N-[3-[[2-[[4-(4-acetyl-1-piperazinyl)-2-methoxyphenyl]amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]phenyl]-2-propenamide AVL-301Medchemexpress.com
Product Overview: An irreversible inhibitor of mutant forms of EGFR including T790M (Ki = 21.5 nM) with minimal activity at the wild-type EGFR (Ki = 303.3 nM); inhibits the proliferation of NSCLC cells expressing mutant EGFR (GI50s = 7-32 nM) and demonstrates anti-tumor ac
Shipping: wet ice
CAS NO: 1061318-81-7 Product: Debio 0932
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C27H28F3N7O3
SMILES: O=C(C=C)NC1=CC=CC(NC2=NC(NC3=CC=C(N4CCN(C(C)=O)CC4)C=C3OC)=NC=C2C(F)(F)F)=C1NOD-like Receptor NLR) inhibitors
Molecular Weight: 555.6
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/55/8/3720.abstract
