CHIR124

Product Name: CHIR124
Synonyms: 4-[(3S)-1-azabicyclo[2.2.2]oct-3-ylamino]-3-(1H-benzimidazol-2-yl)-6-chloro-2(1H)-quinolinoneMedchemexpress
Product Overview: A selective, cell-permeable, quinolone-based inhibitor of Chk1 (IC50 = 0.3 nM versus 0.7 µM for Chk1 and Chk2, respectively); inhibits p53-mutant solid tumor cell growth in synergy with topoisomerase I poisons or ionizing radiation, potentiating tum
Shipping: wet ice
CAS NO: 0 GNE-617 (hydrochloride)
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C23H22ClN5O
SMILES: O=C(C(C1=NC2=C(C=CC=C2)N1)=C3N[[email protected]@H]4CN5CCC4CC5)NC6=C3C=C(Cl)C=C6SARS-CoV inhibitors
Molecular Weight: 419.9
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://www.bloodjournal.org/content/127/13/1629