Product Name: CAY10681
Synonyms: 4-(4-bromophenyl)-4,5-dihydro-5-[3-(1H-imidazol-1-yl)propyl]-3-phenyl-1-(phenylmethyl)-pyrrolo[3,4-c]pyrazol-6(1H)-oneMedchemexpress
Product Overview: A dual modulator of p53-MDM2 interaction and NF-κB signaling; binds MDM2 (Ki = 250 nM), reducing MDM2-mediated turnover of p53; inhibits phosphorylation of IκBα and dose-dependently reduces nuclear accumulation of p65; inhibits cancer ce
Shipping: wet ice
CAS NO: 432001-69-9 Product: Skp2 Inhibitor C1
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C30H26BrN5O
SMILES: O=C1N(CCCN2C=CN=C2)C(C3=CC=C(Br)C=C3)C4=C1N(CC5=CC=CC=C5)N=C4C6=CC=CC=C6p97 inhibitors
Molecular Weight: 552.5
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/58/3/1630.abstract