Bisindolylmaleimide XI (hydrochloride)
Bisindolylmaleimide XI (hydrochloride)

Bisindolylmaleimide XI (hydrochloride)

Product Name: Bisindolylmaleimide XI (hydrochloride)
Synonyms: 3-[8-[(dimethylamino)methyl]-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione, monohydrochloride BIM XI Medchemexpress
Product Overview: A selective, cell-permeable PKC inhibitor that displays 10-fold greater selectivity for PKCα (IC50 = 9 nM) and 4-fold greater selectivity for PKCβI (IC50 = 28 nM) over Ca2+-independent PKCε (IC50 = 108 nM); prevents T-cell activation an
Shipping: wet ice
CAS NO: 953769-46-5 BLZ945
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C28H28N4O2 • HCl
SMILES: O=C(NC1=O)C(C2=CNC3=C2C=CC=C3)=C1C4=C5N(CCC(CN(C)C)C5)C6=CC=CC=C64.ClPI3K_Akt_mTOR inhibitors
Molecular Weight: 489
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://www.bloodjournal.org/content/129/11/1514