Bisindolylmaleimide VIII (acetate)
Bisindolylmaleimide VIII (acetate)

Bisindolylmaleimide VIII (acetate)

Product Name: Bisindolylmaleimide VIII (acetate)
Synonyms: 3-[1-(3-aminopropyl)-1H-indol-3-yl]-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione, acetate BIM VIII Web Site click
Product Overview: A selective PKC inhibitor (IC50 = 158 nM for rat brain PKC) that acts at the ATP binding site of PKC; exhibits PKC isozyme specificity with preference for PKCα over PKCβI, PKCβII, PKCγ, or PKCε (IC50s = 53, 195, 163, 213, and
Shipping: wet ice
CAS NO: 1319207-44-7 Product: CC0651
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C24H22N4O2 • C2H4O2
SMILES: O=C(N1[H])C(C2=CN(C)C3=C2C=CC=C3)=C(C4=CN(CCCN)C5=C4C=CC=C5)C1=O.CC(O)=O15-PGDH inhibitors
Molecular Weight: 458.5
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/54/10/4343.abstract