AZD 9291
AZD 9291

AZD 9291

Product Name: AZD 9291
Synonyms: N-[2-[[2-(dimethylamino)ethyl]methylamino]-4-methoxy-5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]
Product Overview: An irreversible inhibitor of EGFR sensitizing and T790M resistance mutations (IC50s = 15-17 nM) while sparing the wild-type EGFR (IC50 = 480 nM); inhibits tumor growth in a xenograft mouse model at oral doses of 5-10 mg/kgAZD 9291 is an irreversible inhib
Shipping: wet ice
CAS NO: 131-69-1 Product: Phthalylsulfacetamide
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C28H33N7O2
SMILES: CN(CCN(C)C)C1=C(NC(C=C)=O)C=C(NC2=NC=CC(C3=CN(C)C4=C3C=CC=C4)=N2)C(OC)=C1Histamine Receptor inhibitors
Molecular Weight: 499.6
Formulation: A crystalline solid
Purity: ≥98%PubMed ID: