AZD 2461
AZD 2461

AZD 2461

Product Name: AZD 2461
Synonyms: 4-[[4-fluoro-3-[(4-methoxy-1-piperidinyl)carbonyl]phenyl]methyl]-1(2H)-phthalazinoneWeb Site click
Product Overview: A PARP inhibitor (IC50 = 5 nM) with low affinity for the P-glycoprotein drug efflux transporter; induces a loss of p53 binding protein 1 expression in mice with KB1P tumors at 100 mg/kgThe poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with
Shipping: wet ice
CAS NO: 246256-50-8 Product: 5(6)-TAMRA SE
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C22H22FN3O3
SMILES: O=C1C2=CC=CC=C2C(CC3=CC(C(N4CCC(OC)CC4)=O)=C(F)C=C3)=NN1GSK-3 inhibitors
Molecular Weight: 395.4
Formulation: A crystalline solid
Purity: ≥95%PubMed ID: