AZ191
AZ191

AZ191

Product Name: AZ191
Synonyms: N-​[2-​methoxy-​4-​(4-​methyl-​1-​piperazinyl)​phenyl]​-​4-​(1-​methyl-​1H-​pyrrolo[2,​3-​c]​pyridin-​3-​yl)​-2-​pyrimidinamineMedchemexpress.com
Product Overview: A DYRK1B inhibitor (IC50 = 17 nM) that demonstrates 5-fold and 110-fold selectivity against the related family members DYRK1A and DYRK2, respectively; used as a probe to elucidate the mechanism of DYRK1B regulation of cell cycle progressionDual-specificit
Shipping: wet ice
CAS NO: 501437-28-1 BI-D1870
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C24H27N7O
SMILES: CN1CCN(C2=CC=C(NC3=NC=CC(C4=CN(C)C5=C4C=CN=C5)=N3)C(OC)=C2)CC1Adenylate Cyclase inhibitors
Molecular Weight: 429.5
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://www.bloodjournal.org/content/129/2/171