AMG 706
AMG 706

AMG 706

Product Name: AMG 706
Synonyms: N-(2,3-dihydro-3,3-dimethyl-1H-indol-6-yl)-2-[(4-pyridinylmethyl)amino]-3-pyridinecarboxamide, diphosphate MotesanibWeb Site click
Product Overview: A multikinase inhibitor that predominantly targets receptor tyrosine kinases, including VEGFR1, VEGFR2, VEGFR3, c-Kit, PDGFR, and RET (IC50s = 2, 3, 6, 8, 84, and 59 nM, respectively); blocks VEGF-induced angiogenesis in the rat corneal model and induces
Shipping: wet ice
CAS NO: 5947-49-9 Product: Podocarpic acid
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C22H23N5O • 2H3PO4
SMILES: O=C(NC1=CC=C(C(C)(C)CN2)C2=C1)C3=C(NCC4=CC=NC=C4)N=CC=C3.OP(O)(O)=O.OP(O)(O)=OEukaryotic Initiation Factor eIF) inhibitors
Molecular Weight: 569.4
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/55/2/696.abstract