Product Name: AG-879
Synonyms: 3-[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]-2-cyano-2E-propenethioamide Tyrphostin
Product Overview: A tyrphostin compound that inhibits nerve growth factor (NGF)-dependent TrkA tyrosine phosphorylation in PC-12 cells (IC50 = ~40μM), HER2-ErbB2 kinase in several breast and ovarian cancer cell lines (IC50 = ~0.5 μM), and the VEGF receptor FLK1 (IC50
Shipping: wet ice
CAS NO: 606101-58-0 MK-0773
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C18H24N2OS
SMILES: CC(C)(C)C1=C(O)C(C(C)(C)C)=CC(/C=C(C(N)=S)C#N)=C1Haspin Kinase inhibitors
Molecular Weight: 316.5
Formulation: A crystalline solid
Purity: ≥95%PubMed ID: