AD57 (hydrochloride)
AD57 (hydrochloride)

AD57 (hydrochloride)

Product Name: AD57 (hydrochloride)
Synonyms: N-[4-[4-amino-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl]phenyl]-N-[3-(trifluoromethyl)phenyl]-urea, monohydrochlorideWeb Site:Medchemexpress
Product Overview: A polypharmacological cancer therapeutic; potently inhibits Ret (IC50 = 2 nM) and reduces the activity of numerous other kinases by more than 80% when given at 1 μM in Drosophila; interferes with kinases downstream of Ret, including Src, Raf, and S6KCo
Shipping: wet ice
CAS NO: 875051-72-2 Product: PF-01247324
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C22H20F3N7O • HCl
SMILES: CC(C)N1C2=NC=NC(N)=C2C(C3=CC=C(NC(NC4=CC(C(F)(F)F)=CC=C4)=O)C=C3)=N1.ClAminopeptidase inhibitors
Molecular Weight: 491.9
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/54/10/4484.abstract