Product Name: ABT-199
Synonyms: 4-[4-[[2-(4-chlorophenyl)-4,4-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[3-nitro-4-[[(tetrahydro-2H-pyran-4-yl)methyl]amino]phenyl]sulfonyl]-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)-benzamide Web Site click
Product Overview: A BH3 mimetic that selectively inhibits Bcl-2 (Ki 3-fold less avidly to the related family proteins, Bcl-XL and Bcl-W (Kis = 48 and 245 nM, respectively); inhibits the growth of Bcl-2-dependent cell lines and in vivo tumor xenografts and demonstrates ant
Shipping: wet ice
CAS NO: 367273-07-2 Product: AGN 195183
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C45H50ClN7O7S
SMILES: ClC1=CC=C(C2=C(CN3CCN(C4=CC(OC5=CN=C(NC=C6)C6=C5)=C(C(NS(C7=CC([N+]([O-])=O)=C(NCC8CCOCC8)C=C7)(=O)=O)=O)C=C4)CC3)CCC(C)(C)C2)C=C1TNF-alpha inhibitors
Molecular Weight: 868.4
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/58/3/1693.abstract
