9-amino Camptothecin
9-amino Camptothecin

9-amino Camptothecin

Product Name: 9-amino Camptothecin
Synonyms: (4S)-10-amino-4-ethyl-4-hydroxy-1H-pyrano[3,4:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione NSC 603071Web Site click
Product Overview: A topoisomerase I inhibitor that is cytotoxic to HT-29 cells (IC50 = 19 nM), induces DNA damage in whole cells (at 85 nM), and demonstrates significant anti-tumor activityDNA topoisomerases relax supercoiled DNA during replication, transcription, recombin
Shipping: wet ice
CAS NO: 91037-65-9 Arg-Gly-Asp-Ser
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C20H17N3O4
SMILES: O=C([[email protected]@]1(CC)O)OCC2=C1C=C(C(N=C(C=CC=C3N)C3=C4)=C4C5)N5C2=OULK inhibitors
Molecular Weight: 363.4
Formulation: A crystalline solid
Purity: ≥95%PubMed ID:http://aac.asm.org/content/54/8/3520.abstract