(5Z)-7-Oxo Zeaenol
(5Z)-7-Oxo Zeaenol

(5Z)-7-Oxo Zeaenol

Product Name: (5Z)-7-Oxo Zeaenol
Synonyms: (3S,5Z,8S,9S,11E)-3,4,9,10-tetrahydro-8,9,16-trihydroxy-14-methoxy-3-methyl-1H-2-benzoxacyclotetradecin-1,7(8H)-dione FR148083 Web Site:Medchemexpress
Product Overview: A natural resorcylic lactone derived from fungi that selectively inhibits purified TAK1 (IC50 = 8.1 nM when co-expressed with the TAK1-binding protein, TAB1); irreversibly blocks IL-1-induced activation of TAK1, NF-κB, and JNK/p38 (IC50s = 65-83 nM)
Shipping: wet ice
CAS NO: 245342-14-7 Product: LED209
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C19H22O7
SMILES: O=C1[[email protected]@H](O)[[email protected]@H](O)C/C=C/C2=CC(OC)=CC(O)=C2C(O[[email protected]@H](C)C/C=C1)=OMembrane_Transporter/Ion_Channel_Compound_Library inhibitors
Molecular Weight: 362.4
Formulation: A white solid
Purity: ≥99%PubMed ID:http://aac.asm.org/content/55/11/5018.abstract