Product Name: 3-Deazaneplanocin A (hydrochloride)
Synonyms: 5R-(4-amino-1H-imidazo[4,5-c]pyridin-1-yl)-3-(hydroxymethyl)-3-cyclopentene-1S,2R-diol, monohydrochloride 2,3-DMMCWeb Site:Medchemexpress
Product Overview: An analog of 3-deazaadenosine, an inhibitor of SAH hydrolase; depletes EZH2 levels and inhibits trimethylation of lysine 27 on histone H3 in primary human AML cells in a dose-dependent manner (0.2-1 μM); acts synergistically with the pan-HDAC inhibitor
Shipping: wet ice
CAS NO: 330161-87-0 Product: SU6656
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C12H14N4O3 • HCl
SMILES: NC1=NC=CC2=C1N=CN2[C@@H]3C=C(CO)[C@@H](O)[C@H]3O.ClMonoamine Transporter inhibitors
Molecular Weight: 298.7
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/57/7/3326.abstract