Product Name: dBET1
Synonyms: (6S)-4-(4-chlorophenyl)-N-[4-[[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetyl]amino]butyl]-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamideMedchemexpress
Product Overview: A hybrid molecule that combines (+)-JQ1 and lenalidomide; induces cereblon-dependent BET protein degradation in vitro (EC50 = 430 nM) and in vivo and delays leukemia progression in micedBET1 is a hybrid molecule that combines (+)-JQ1 (Item No. 11187) and
Shipping: wet ice
CAS NO: 315183-21-2 Product: PAC-1
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C38H37ClN8O7S
SMILES: CC1=NN=C2[C@H](CC(NCCCCNC(COC3=CC=CC(C(N4C5C(NC(CC5)=O)=O)=O)=C3C4=O)=O)=O)N=C(C6=CC=C(Cl)C=C6)C7=C(SC(C)=C7C)N21IRE1 inhibitors
Molecular Weight: 785.3
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/47/12/3795.abstract
