Product Name: VX-745
Synonyms: 5-(2,6-dichlorophenyl)-2-[(2,4-difluorophenyl)thio]-6H-pyrimido[1,6-b]pyridazin-6-oneMedchemexpress
Product Overview: A selective inhibitor of p38α MAPK (IC50 = 10 nM) that blocks IL-1β and TNF-α release in whole blood in vitro (IC50s = 150 and 180 nM, respectively)p38α is a member of the mitogen-activated protein kinase (MAPK) family of serine/thr
Shipping: wet ice
CAS NO: 1206161-97-8 Product: GLPG0634
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C19H9Cl2F2N3OS
SMILES: ClC1=C(C2=C(C=CC(SC3=CC=C(F)C=C3F)=N4)N4C=NC2=O)C(Cl)=CC=C1MyD88 inhibitors
Molecular Weight: 436.3
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/59/1/702.abstract
