Product Name: Tpl2 Kinase Inhibitor
Synonyms: 4-[(3-chloro-4-fluorophenyl)amino]-6-[(3-pyridinylmethyl)amino]-1,7-naphthyridine-3-carbonitrile c-Cot Kinase Inhibitor Medchemexpress.com
Product Overview: A reversible inhibitor of Tpl2 (pIC50 = 7.3); blocks LPS-induced TNF-α production in mice and human monocytesTpl2 kinase inhibitor is a reversible inhibitor of tumor progression locus 2 (Tpl2; pIC50 = 7.3). It blocks LPS-induced TNF-α product
Shipping: wet ice
CAS NO: 885060-08-2 Product: ARRY-520 (R enantiomer)
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C21H14ClFN6
SMILES: FC(C=C1)=C(Cl)C=C1NC2=C(C#N)C=NC(C=N3)=C2C=C3NCC4=CN=CC=C45-HT Receptor inhibitors
Molecular Weight: 404.8
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/60/3/1450.abstract
