Product Name: THZ1
Synonyms: N-[3-[[5-chloro-4-(1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-4-[[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]amino]-benzamideMedchemexpress
Product Overview: A covalent Cdk7 inhibitor (IC50s = 3.2-15.6 nM in vitro) that displays broad anti-proliferative activity against cancer cell lines, particularly T-ALL cell lines with characteristic misregulation of T cell lineage-specific transcription factorsTHZ1 is a C
Shipping: wet ice
CAS NO: 540737-29-9 Product: Tofacitinib (citrate)
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C31H28ClN7O2
SMILES: CN(C/C=C/C(NC1=CC=C(C(NC2=CC(NC3=NC=C(Cl)C(C4=CNC5=C4C=CC=C5)=N3)=CC=C2)=O)C=C1)=O)CP-glycoprotein inhibitors
Molecular Weight: 566.1
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/60/5/2807.abstract
