Product Name: Sulindac sulfide
Synonyms: 5-fluoro-2-methyl-1Z-[[4-(methylthio)phenyl]methylene]-1H-indene-3-acetic acidWeb Site click
Product Overview: A metabolite of sulindac that inhibits both COX-1 and COX-2 (IC50s = 1.9 and 1.21 µM, respectively); also inhibits aldose reductase (IC50 = 279 nM), blocking NADPH-dependent reduction of glucose to sorbitol, and reducing type 2 diabetic complication
Shipping: wet ice
CAS NO: 195514-80-8 AP20187
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C20H17FO2S
SMILES: O=C(O)CC(C1=C/2C=CC(F)=C1)=C(C)C2=C/C3=CC=C(SC)C=C3Cathepsin inhibitors
Molecular Weight: 340.4
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://www.bloodjournal.org/content/129/13/1745
