Product Name: Semagacestat
Synonyms: (2S)-2-hydroxy-3-methyl-N-[(1S)-1-methyl-2-oxo-2-[[(1S)-2,3,4,5-tetrahydro-3-methyl-2-oxo-1H-3-benzazepin-1-yl]amino]ethyl]-butanamide LY450139Medchemexpress
Product Overview: A potent inhibitor of γ-secretase that blocks the production of Aβ38, Aβ40, and Aβ42 with IC50 values of 12.0, 12.1, and 10.9 nM, respectively; also blocks Notch signaling (IC50 = 14.1 nM); modulates γ-secretase activity in vivo
Shipping: wet ice
CAS NO: 179324-69-7 Bortezomib
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C19H27N3O4
SMILES: O=C1N(CCC(C=CC=C2)=C2[C@@H]1NC([C@H](C)NC([C@@H](O)C(C)C)=O)=O)CInterleukin Related inhibitors
Molecular Weight: 361.4
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://www.bloodjournal.org/content/116/21/246
