Product Name: SR 2211
Synonyms: 2-fluoro-4’-[[4-(4-pyridinylmethyl)-1-piperazinyl]methyl]-α,α-bis(trifluoromethyl)-[1,1’-biphenyl]-4-methanolWeb Site：Medchemexpress
Product Overview: Selectively binds RORγ (Ki = 105 nM), acting as an inverse agonist of constitutive in vitro RORγ activity (IC50 = 320 nM); significantly inhibits gene expression of IL-17 and IL-23 receptor in activated EL-4 mouse T lymphocytes when given at 5
Shipping: wet ice
CAS NO: 1375465-91-0 ACY-738
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C26H24F7N3O
SMILES: OC(C(F)(F)F)(C1=CC(F)=C(C2=CC=C(CN3CCN(CC4=CC=NC=C4)CC3)C=C2)C=C1)C(F)(F)FPKC inhibitors
Molecular Weight: 527.5
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://www.bloodjournal.org/content/129/19/2702
