Product Name: SL 327
Synonyms: α-[amino[(4-aminophenyl)thio]methylene]-2-(trifluoromethyl)-benzeneacetonitrileWeb Site：Medchemexpress
Product Overview: A selective inhibitor of MEK1 and MEK2 (IC50s = 0.18 and 0.22 μM), the kinases upstream of ERK1/2; rapidly passes the blood-brain barrier and has been used to dissect the effect of RAS/RAF/MEK/ERK signaling pathway inhibition on behaviorThe dual specif
Shipping: wet ice
CAS NO: 931706-15-9 Product: PPQ-102
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C16H12F3N3S
SMILES: N/C(SC1=CC=C(N)C=C1)=C(C#N)C2=CC=CC=C2C(F)(F)FKinase_Inhibitor_Library inhibitors
Molecular Weight: 335.4
Formulation: A crystalline solid
Purity: ≥95% (mixture of cis/trans isomers)PubMed ID:http://aac.asm.org/content/58/7/3853.abstract
Related Posts
Product Name: SL-327
Synonyms: Medchemexpress
Product Overview: SL327 is a selective inhibitor for MEK1/2 with IC50 of 0.18 μM/ 0.22 μM, no activity towards Erk1, MKK3, MKK4, c-JUN, PKC, PKA, or CamKII;capable of transport through the blood-brain barrier.
Shipping: wet ice
CAS NO: 55290-63-6 Product: Atractylodin
Stability: Store at +4 degrees; shelf life 730 days maximum after production
Molecular Formula: C16H12F3N3S
SMILES: MyD88 inhibitors
Molecular Weight: 335.35
Formulation: solution 10mM in DMSO
Purity: 0.98PubMed ID:http://aac.asm.org/content/47/10/3208.abstract