Product Name: SB-705498
Synonyms: N-(2-bromophenyl)-N-[(3R)-1-[5-(trifluoromethyl)-2-pyridinyl]-3-pyrrolidinyl]-ureaMedchemexpress.com
Product Overview: An orally bioavailable, competitive antagonist of the capsaicin-mediated activation of TRPV1 receptors (pKis = 7.6, 7.5, and 7.3 for human, rat, and guinea pig, respectively); induces rapid, reversible inhibition of capsaicin (IC50 = 3 nM)-, acid (pH 5.3)
Shipping: wet ice
CAS NO: 924296-17-3 Product: DUBs-IN-3
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C17H16BrF3N4O
SMILES: BrC1=C(NC(N[C@@H]2CCN(C3=NC=C(C(F)(F)F)C=C3)C2)=O)C=CC=C1Wnt/Hedgehog/Notch_Compound_Library inhibitors
Molecular Weight: 429.2
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/58/7/3650.abstract
