Product Name: SB-505124
Synonyms: 2-[4-(1,3-benzodioxol-5-yl)-2-(1,1-dimethylethyl)-1H-imidazol-5-yl]-6-methyl-pyridineWeb Site：Medchemexpress
Product Overview: Inhibits ALK5- (IC50 = 47 nM), ALK4- (IC50 = 129 nM), and ALK7-dependent activation of downstream SMAD2 and SMAD3 and TGF-β–induced MAP kinase pathway components without altering ALK1-3 or ALK6-induced SMAD signalingSB-505124 inhibits the TGF-&
Shipping: wet ice
CAS NO: 133718-30-6 Product: R 80123
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C20H21N3O2
SMILES: CC(C)(C)C1=NC(C2=CC(OCO3)=C3C=C2)=C(C4=NC(C)=CC=C4)N1TGF-beta) Receptor inhibitors
Molecular Weight: 335.4
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/55/5/2469.abstract
