Product Name: SB 218078
Synonyms: 9,10,11,12-tetrahydro-9,12-epoxy-1H-diindolo[1,2,3-fg:3,2,1-kl]pyrrolo[3,4-i][1,6]benzodiazocine-1,3(2H)-dioneMedchemexpress
Product Overview: An inhibitor of Chk1 that blocks phosphorylation of cdc25 with an IC50 value of 15 nM; releases G2 cell cycle arrest induced by γ-irradiation or topotecanSB 218078 is an inhibitor of checkpoint kinase 1 (Chk1) that blocks phosphorylation of cdc25 wi
Shipping: wet ice
CAS NO: 501951-42-4 Product: SB-705498
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C24H15N3O3
SMILES: O=C(NC1=O)C2=C1C3=C4C5=C2C6=C(C=CC=C6)N5C7OC(CC7)N4C8=C3C=CC=C8Trk Receptor inhibitors
Molecular Weight: 393.4
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/60/6/3563.abstract
