Product Name: Rucaparib (phosphate)
Synonyms: 8-fluoro-1,3,4,5-tetrahydro-2-[4-[(methylamino)methyl]phenyl]-6H-pyrrolo[4,3,2-ef][2]benzazepin-6-one, phosphate AG-014699 Medchemexpress.com
Product Overview: A potent, cell-permeable inhibitor of PARP1 (Ki = 50s = 1.3-5.5 μM); arrests tumor growth in mice bearing epigenetically silenced BRCA1 UACC3199 xenograft tumorsPoly(ADP-ribose) polymerases (PARPs) are activated by DNA single- and double-strand breaks
Shipping: wet ice
CAS NO: 194423-06-8 Product: CL-387785
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C19H18FN3O • H3PO4
SMILES: O=C1NCCC2=C(C3=CC=C(CNC)C=C3)NC4=CC(F)=CC1=C24.OP(O)(O)=OAnti-infection_Compound_Library inhibitors
Molecular Weight: 421.4
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/58/2/1240.abstract
