Product Name: Ro 4929097
Synonyms: N1-[(7S)-6,7-dihydro-6-oxo-5H-dibenz[b,d]azepin-7-yl]-2,2-dimethyl-N3-(2,2,3,3,3-pentafluoropropyl)-propanediamideMedchemexpress.com
Product Overview: A potent, selective inhibitor of γ-secretase (IC50 = 4 nM) that blocks both Aβ40 and Notch processing (IC50s = 14 and 5 nM, respectively); orally active against cancer xenograft models, altering gene expression related to angiogenesis and cell
Shipping: wet ice
CAS NO: 98791-67-4 Product: Bay-K-8644 ((R)-(+)-)
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C22H20F5N3O3
SMILES: O=C(C(C)(C)C(NCC(F)(F)C(F)(F)F)=O)N[C@@H]1C(NC2=C(C=CC=C2)C3=C1C=CC=C3)=OMineralocorticoid Receptor inhibitors
Molecular Weight: 469.4
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/47/11/3384.abstract
