Product Name: Radotinib
Synonyms: 4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[[4-(2-pyrazinyl)-2-pyrimidinyl]amino]-benzamide IY-5511Web Site click
Product Overview: A selective second-generation Bcr-Abl tyrosine kinase inhibitor (IC50 = 32.5 nM); targets PDGFRα and β (IC50s = 75.5 nM and 130 nM, respectively); reduces viability and promotes differentiation in human acute myeloid leukem
Shipping: wet ice
CAS NO: 23491-44-3 Product: Hoechst 33258
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C27H21F3N8O
SMILES: CC(C=CC(C(NC1=CC(N2C=NC(C)=C2)=CC(C(F)(F)F)=C1)=O)=C3)=C3NC4=NC(C5=NC=CN=C5)=CC=N4IRAK inhibitors
Molecular Weight: 530.5
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/59/12/7899.abstract
