Product Name: Quizartinib
Synonyms: N-[5-(1,1-dimethylethyl)-3-isoxazolyl]-N-[4-[7-[2-(4-morpholinyl)ethoxy]imidazo[2,1-b]benzothiazol-2-yl]phenyl]-urea ACMedchemexpress
Product Overview: A selective FLT3 inhibitor (Kd = 1.6 nM) that inhibits the proliferation of MV4-11 cells both in vitro (IC50 = 0.56 nM) and in in vivo mouse models of FLT3-ITD acute myeloid leukemiaQuizartinib is an inhibitor of FMS-related tyrosine kinase 3 (FLT3; Kd =
Shipping: wet ice
CAS NO: 176957-55-4 Product: CCT007093
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C29H32N6O4S
SMILES: O=C(NC1=NOC(C(C)(C)C)=C1)NC2=CC=C(C3=CN4C(SC5=C4C=CC(OCCN6CCOCC6)=C5)=N3)C=C2GPCR/G_protein_Compound_Library inhibitors
Molecular Weight: 560.7
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/58/11/6581.abstract
