Product Name: Pyrrophenone
Synonyms: N-[[(2S,4R)-1-[2-(2,4-difluorobenzoyl)benzoyl]-4-[(triphenylmethyl)thio]-2-pyrrolidinyl]methyl]-4-[(Z)-(2,4-dioxo-5-thiazolidinylidene)methyl]-benzamideWeb Site click
Product Overview: Reversible, selective inhibitor of cPLA2 with an IC50 value of 4.2 nM in enzyme assays; potently blocks the release of AA and the production of PGE2 and LTC4 in cells (IC50 = 24, 25, and 14 nM, respectively)The group IVA phospholipase A2 (PLA2), known as
Shipping: wet ice
CAS NO: 1332708-14-1 PF-4840154
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C49H37F2N3O5S2
SMILES: FC(C=C1F)=CC=C1C(C2=CC=CC=C2C(N3[C@H](CNC(C4=CC=C(/C=C5C(NC(S5)=O)=O)C=C4)=O)C[C@@H](SC(C6=CC=CC=C6)(C7=CC=CC=C7)C8=CC=CC=C8)C3)=O)=OADC Cytotoxin inhibitors
Molecular Weight: 850
Formulation: A crystalline solid
Purity: ≥95%PubMed ID:http://www.bloodjournal.org/content/126/23/1306
