Product Name: Phenamil (methanesulfonate)
Synonyms: 3,5-diamino-6-chloro-N-[imino(phenylamino)methyl]-2-pyrazinecarboxamide, monomethanesulfonateWeb Site click
Product Overview: A second generation analog of amiloride that inhibits TRPP3-mediated Ca2+-activated (IC50 = 0.14 μM) and ENaC (IC50 = 10 nM); inhibits active sodium transport of human and ovine bronchial epithelial cells (IC50s = 75 and 116 nM, respectively)Transient
Shipping: wet ice
CAS NO: 1802977-61-2 GNE-140 (racemate)
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C12H12ClN7O • CH3SO3H
SMILES: ClC1=C(N)N=C(N)C(C(NC(NC2=CC=CC=C2)=N)=O)=N1.CS(=O)(O)=OADC Linker inhibitors
Molecular Weight: 401.8
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://www.bloodjournal.org/content/129/23/3130
