Product Name: Pelitinib
Synonyms: N-[4-[(3-chloro-4-fluorophenyl)amino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2E-butenamide EKB-569Medchemexpress
Product Overview: A cyanoquinoline that irreversibly inhibits the receptor tyrosine kinases EGFR (IC50 = 39 nM) and HER2 (IC50 = 1.2 μM); disrupts Akt and MAPK pathways, inducing apoptosis and suppressing the growth of tumor cell linesPelitinib is a cyanoquinoline that
Shipping: wet ice
CAS NO: 321674-73-1 Product: BIBR 1532
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C24H23ClFN5O2
SMILES: FC(C=C1)=C(Cl)C=C1NC2=C(C#N)C=NC3=C2C=C(NC(/C=C/CN(C)C)=O)C(OCC)=C3TRP Channel inhibitors
Molecular Weight: 467.9
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/60/5/3032.abstract
