Product Name: PLX4032
Synonyms: N-[3-[[5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide RG-7204 Web Site click
Product Overview: An orally bioavailable, ATP-competitive inhibitor of mutant V600E and wild type B-Raf kinases (IC50s = 31 and 100 nM, respectively); inhibits cell proliferation in a variety of cell lines expressing B-RafV600E and is effective against the growth of tumors
Shipping: wet ice
CAS NO: 243984-11-4 TAK-242
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C23H18ClF2N3O3S
SMILES: ClC1=CC=C(C2=CN=C(NC=C3C(C4=C(F)C=CC(NS(=O)(CCC)=O)=C4F)=O)C3=C2)C=C1HCV Protease inhibitors
Molecular Weight: 489.9
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://www.bloodjournal.org/content/129/13/1881
