Product Name: PIK-III
Synonyms: 4-(cyclopropylmethyl)-N2-4-pyridinyl-[4,5-bipyrimidine]-2,2-diamine Vacuolar Protein Sorting 34 Inhibitor 2 Medchemexpress
Product Overview: A selective inhibitor of Vps34 (PI3K type 3; IC50 = 18 nM); acutely inhibits autophagy and de novo lipidation of LC3, leading to stabilization of autophagy substratesPIK-III is an inhibitor of the type 3 phosphatidylinositol 3-kinase (PI3K) vacuolar prote
Shipping: dry ice
CAS NO: 1103522-45-7 Product: ACT-132577
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C17H17N7
SMILES: NC(N=C1)=NC(CC2CC2)=C1C3=CC=NC(NC4=CC=NC=C4)=N3FLT3 inhibitors
Molecular Weight: 319.4
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/49/1/414.abstract
