Product Name: PF-562271 (besylate)
Synonyms: N-[3-[[[2-[(2,3-dihydro-2-oxo-1H-indol-5-yl)amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]methyl]-2-pyridinyl]-N-methyl-methanesulfonamide, monobenzenesulfonateMedchemexpress.com
Product Overview: An ATP-competitive, reversible inhibitor of FAK (IC50 = 1.5 nM) and PYK2 (IC50 = 14 nM); inhibits FAK phosphorylation (EC50 = 93 ng/ml) in glioblastoma-bearing mice and has been shown to regress tumors in multiple xenograft modelsFocal adhesion kinase (FA
Shipping: wet ice
CAS NO: 1786-81-8 Product: Prilocaine (hydrochloride)
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C21H20F3N7O3S • C6H6O3
SMILES: CN(S(C)(=O)=O)C1=C(CNC2=C(C(F)(F)F)C=NC(NC3=CC=C(NC(C4)=O)C4=C3)=N2)C=CC=N1.OS(C5=CC=CC=C5)(=O)=OBradykinin Receptor inhibitors
Molecular Weight: 665.7
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/59/5/2886.abstract
