Product Name: PF-3758309
Synonyms: N-[(1S)-2-(dimethylamino)-1-phenylethyl]-4,6-dihydro-6,6-dimethyl-3-[(2-methylthieno[3,2-d]pyrimidin-4-yl)amino]-pyrrolo[3,4-c]pyrazole-5(1H)-carboxamide Web Site click
Product Overview: An ATP-competitive inhibitor of PAK4, preventing the phosphorylation of the PAK4 substrate GEF-H1 (IC50 = 1.3 nM) and blocking anchorage-independent growth of a panel of tumor cell lines (IC50 = 4.7 nM); blocks the growth of multiple human tumor xenograft
Shipping: wet ice
CAS NO: 867331-82-6 Product: TG 100801
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C25H30N8OS
SMILES: CN(C)C[C@@H](NC(N1CC(C(NC2=NC(C)=NC3=C2SC=C3)=NN4)=C4C1(C)C)=O)C5=CC=CC=C5c-Met_HGFR inhibitors
Molecular Weight: 490.6
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/60/6/3653.abstract
