Product Name: PF-299804
Synonyms: N-[4-[(3-chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-4-(1-piperidinyl)-(2E)-butenamide Dacomitinib Medchemexpress
Product Overview: An irreversible pan-ErbB receptor tyrosine kinase inhibitor (IC50s = 6, 45.7, and 73.7 nM for ErbB1, ErbB2, and ErbB4, respectively); demonstrates antitumor activity in various tumor xenograft models expressing either wild-type ErbB or mutant ErbB family
Shipping: wet ice
CAS NO: 1187020-80-9 lumateperone (Tosylate)
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C24H25ClFN5O2
SMILES: O=C(NC1=C(OC)C=C(N=CN=C2NC3=CC(Cl)=C(F)C=C3)C2=C1)/C=C/CN4CCCCC4MAPKAPK2 MK2) inhibitors
Molecular Weight: 469.9
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/54/4/1590.abstract
