Product Name: OSI-027
Synonyms: trans-4-[4-amino-5-(7-methoxy-1H-indol-2-yl)imidazo[5,1-f][1,2,4]triazin-7-yl]-cyclohexanecarboxylic acidMedchemexpress
Product Overview: An inhibitor of the catalytic site of mTOR, inhibiting both mTORC1 and mTORC2 (IC50s = 22 and 65 nM, respectively); prohibits proliferation, induces autophagy, and potentiates apoptosis in BCR-ABL transformed cells and other cancer cells at 10 µM; e
Shipping: wet ice
CAS NO: 943962-47-8 Product: BMS-303141
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C21H22N6O3
SMILES: NC1=NC=NN2C1=C(C3=CC4=C(C(OC)=CC=C4)N3)N=C2[C@@H]5CC[C@@H](C(O)=O)CC5Steroids inhibitors
Molecular Weight: 406.4
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/59/4/1876.abstract
