Product Name: ONX 0912
Synonyms: O-methyl-N-[(2-methyl-5-thiazolyl)carbonyl]-L-seryl-O-methyl-N-[(1S)-2-[(2R)-2-methyl-2-oxiranyl]-2-oxo-1-(phenylmethyl)ethyl]-L-serinamide Medchemexpress
Product Overview: An orally bioavailable proteasome inhibitor; targets the chymotrypsin-like activity of the 20S proteasome subunits β5 and LMP7 (IC50s = 36 and 82 nM, respectively); inhibits the growth of multiple myeloma cells at nanomolar concentrationsONX 0912 is
Shipping: wet ice
CAS NO: 781649-09-0 MK-0974
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C25H32N4O7S
SMILES: O=C([C@]1(C)OC1)[C@@H](NC([C@H](COC)NC([C@H](COC)NC(C2=CN=C(C)S2)=O)=O)=O)CC3=CC=CC=C3Prostaglandin Receptor inhibitors
Molecular Weight: 532.6
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/54/1/207.abstract
