Product Name: Necrostatin-2
Synonyms: 5R-[(7-chloro-1H-indol-3-yl)methyl]-3-methyl-2,4-imidazolidinedione Cl-Necrostatin analogMedchemexpress
Product Overview: A potent inhibitor of necroptosis (EC50 = 50 nM); 4-fold more active than the (S)-enantiomer (EC50 = 230 nM)Necrostatin-2 is a potent inhibitor of necroptosis with an EC50 of 50 nM in Jurkat T cells deficient of Fas-associated protein with death domain (F
Shipping: dry ice
CAS NO: 256925-03-8 Product: AL 082D06
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C13H12ClN3O2
SMILES: O=C([C@H](N1)CC2=CNC3=C(Cl)C=CC=C32)N(C)C1=OHCN Channel inhibitors
Molecular Weight: 277.7
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/47/6/1991.abstract
