Product Name: NVP-AUY922
Synonyms: 5-[2,4-dihydroxy-5-(1-methylethyl)phenyl]-N-ethyl-4-[4-(4-morpholinylmethyl)phenyl]-3-isoxazolecarboxamide VER 52296Medchemexpress.com
Product Overview: A Hsp90 inhibitor (IC50 = 21 nM in a FP binding assay) that prevents the proliferation of a range of human cancer cell lines in vitro (GI50s ~ 9nM); 50 mg/kg inhibits tumor growth in a human colon cancer xenograft model by ~50% compared to vehicle control
Shipping: wet ice
CAS NO: 1426802-50-7 ROR gamma-t-IN-1
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C26H31N3O5
SMILES: OC1=CC(O)=C(C(C)C)C=C1C2=C(C3=CC=C(CN4CCOCC4)C=C3)C(C(NCC)=O)=NO215-PGDH inhibitors
Molecular Weight: 465.5
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://www.bloodjournal.org/content/118/21/1090
