Product Name: NVP-AEW541 (hydrochloride)
Synonyms: 7-[cis-3-(1-azetidinylmethyl)cyclobutyl]-5-[3-(phenylmethoxy)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine, dihydrochlorideMedchemexpress
Product Overview: A selective IGF-1R kinase inhibitor (IC50 = 0.086 µM); prevents IGF-I-mediated survival and proliferation of MCF-7 cells (IC50 = 0.16 and 1.64 µM, respectively); dose-dependently inhibits tumor growth in a mouse NWT-21 fibrosarcoma tumor model
Shipping: wet ice
CAS NO: 364782-34-3 Cinacalcet (hydrochloride)
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C27H29N5O • 2HCl
SMILES: NC1=C2C(N([C@@H]3C[C@H](CN4CCC4)C3)C=C2C5=CC=CC(OCC6=CC=CC=C6)=C5)=NC=N1.Cl.ClRas inhibitors
Molecular Weight: 512.5
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://www.bloodjournal.org/content/129/16/2212
