Product Name: NCT-503
Synonyms: N-(4,6-dimethyl-2-pyridinyl)-4-[[4-(trifluoromethyl)phenyl]methyl]-1-piperazinecarbothioamideWeb Site：Medchemexpress
Product Overview: A PHGDH inhibitor that blocks serine synthesis from 3-phosphoglycerate in cells (IC50 = 2.5 µM); reduces the production of glucose-derived serine in cells and suppresses the growth of PHGDH-dependent MDA-MB-468 cancer cells both in vitro and in mice
Shipping: wet ice
CAS NO: 486424-20-8 Product: AZD2858
Stability: Store at -20 degrees; shelf life 365 days maximum after production
Molecular Formula: C20H23F3N4S
SMILES: S=C(N1CCN(CC2=CC=C(C(F)(F)F)C=C2)CC1)NC3=NC(C)=CC(C)=C3Cathepsin inhibitors
Molecular Weight: 408.5
Formulation: A solution in methanol
Purity: ≥98%PubMed ID:http://aac.asm.org/content/59/8/4510.abstract
