Product Name: NCT-502
Synonyms: N-(4,6-dimethyl-2-pyridinyl)-4-[5-(trifluoromethyl)-2-pyridinyl]-1-piperazinecarbothioamideMedchemexpress
Product Overview: A selective PHGDH inhibitor that blocks serine synthesis from 3-phosphoglycerate in cells (IC50 = 3.7 µM); reversibly blocks the production of glucose-derived serine in cellsNCT-502 is an inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH), inhibi
Shipping: wet ice
CAS NO: 176708-42-2 Product: KN-92
Stability: Store at -20 degrees; shelf life 365 days maximum after production
Molecular Formula: C18H20F3N5S
SMILES: S=C(N1CCN(C2=NC=C(C(F)(F)F)C=C2)CC1)NC3=NC(C)=CC(C)=C3ADC Linker inhibitors
Molecular Weight: 395.4
Formulation: A solution in methanol
Purity: ≥98%PubMed ID:http://aac.asm.org/content/60/3/1751.abstract
