Product Name: NBI 35965 (mesylate)
Synonyms: (7S)-6-(cyclopropylmethyl)-2-(2,4-dichlorophenyl)-7-ethyl-7,8-dihydro-4-methyl-6H-1,3,6,8a-tetraazaacenaphthylene, monomethanesulfonateMedchemexpress
Product Overview: A selective CRF1 antagonist (Ki = 4 nM); inhibits cAMP accumulation and ACTH production in vitro (pIC50s = 7.1 and 6.9, respectively) and reduces CRF- and stress-induced ACTH production in vivoCorticotropin-releasing hormone, also known as corticotropin-r
Shipping: wet ice
CAS NO: 50-70-4 Product: D-Sorbitol
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C21H22Cl2N4 • CH3SO3H
SMILES: CC1=CC(N(CC2CC2)[C@@H](CC)CN3N=C4C5=CC=C(Cl)C=C5Cl)=C3C4=N1.CS(=O)(O)=OPorcupine inhibitors
Molecular Weight: 497.4
Formulation: A crystalline solid
Purity: ≥95%PubMed ID:http://aac.asm.org/content/58/11/6432.abstract
