Product Name: MS-275
Synonyms: N-[[4-[[(2-aminophenyl)amino]carbonyl]phenyl]methyl]-3-pyridinylmethyl ester, carbamic acid Entinostat Web Site click
Product Overview: An inhibitor of HDACs that preferentially inhibits HDAC1 (IC50 = 300 nM) over HDAC3 (IC50 = 8 μM); does not inhibit HDAC8; induces p21/CIP1/WAF1, slowing cell growth, differentiation, and tumor development in vivoMS-275 is an inhibitor of histone deace
Shipping: wet ice
CAS NO: 154447-36-6 LY294002
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C21H20N4O3
SMILES: O=C(NCC1=CC=C(C(NC2=C(N)C=CC=C2)=O)C=C1)OCC3=CC=CN=C3Monocarboxylate Transporter inhibitors
Molecular Weight: 376.4
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://www.bloodjournal.org/content/129/14/1887
