Product Name: ML-323
Synonyms: 5-methyl-2-[2-(1-methylethyl)phenyl]-N-[[4-(1H-1,2,3-triazol-1-yl)phenyl]methyl]-4-pyrimidinamineMedchemexpress
Product Overview: A selective inhibitor of the USP1-UAF1 deubiquitinase complex activity (IC50 = 76 nM); potentiates cisplatin cytotoxicity in NSCLC H596 cells and U2OS osteosarcoma cells by targeting the TLS and FA DNA damage response pathwaysThe USP1 deubiquitinating enz
Shipping: wet ice
CAS NO: 1426944-49-1 Product: HBX 19818
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C23H24N6
SMILES: CC(C)C1=CC=CC=C1C2=NC=C(C)C(NCC3=CC=C(N4N=NC=C4)C=C3)=N2NOD-like Receptor NLR) inhibitors
Molecular Weight: 384.5
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/59/1/53.abstract
